منابع مشابه
Open-system approaches to gene expression in the CNS.
Where we started In the present era of the nearing completion of the nucleotide sequences of the human genome and of several model organisms, it is easy to overlook the common viewpoint of 20 years ago, especially among neuroscientists. It was clear at that time intellectually that the genome encoded the protein set and that the proteins provided the hardware for the biochemical operation of th...
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ADAM metalloprotease-disintegrins share a common modular structure of functional domains for proteolytic, cell adhesion, and signaling interactions. The metalloprotease domain of oughly half of the known ADAMs contain an intact consensus metzincin catalytic site, and they are thus thought to function as active metalloproteases. The types of interactions mediated by ADAMs are expressly conspicu...
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e aim of this thesis is develop methods to extract information from high-dimensionality data and to apply in looking at gene-gene and gene-protein interactions in Acute Myeloid Leukemia (AML). e in silico methods developed can be used with data from other systems. e thesis gives an overview of the field for network inference and deconvolution methods, as well as a brief background on the bio...
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Primary CNS lymphoma is an aggressive form of non-Hodgkin lymphoma whose growth is restricted to the central nervous system. We used cDNA microarray analysis to compare the gene expression signature of primary CNS lymphomas with nodal large B-cell lymphomas. Here we show that while individual cases of primary CNS lymphomas may be classified as germinal center B-cell, activated B-cell, or type 3...
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Fish farming in recirculating aquaculture systems (RAS) has been expanding in the recent years, but the effects of water reuse are not well known. The aim of the present study was to compare the growth parameters, stress response and muscle stress- and growth- related gene expression of rainbow trout (Oncorhynchus mykiss) in open system (OS) versus water reuse system (WRS). For this purpose, yo...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 2001
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.21-21-08306.2001